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8 clinical pharmacology of cannabinoids in early phase drug development recreational and medical use of cannabis cannabis sativa l is one of the oldest plants used for industrial recreational and medical purposes the fibers of the cannabis plant have been used for the production of rope cloths and paper and its seeds for soap and oil24 clinical pharmacology of cannabinoids in early phase drug development cannabis dosages were pooled into lower medium and higher dosages the lower dose was chosen to be a dose lower than 7 mg roughly corre sponding to half a cigarette the medium dose lay between 7 mg and 18clinical pharmacology of cannabinoids in early phase drug development by hillie henka zuurman get pdf 34 kb abstract although cannabis is especially known for its recreational use as a soft drug its potential therapeutic properties have been recognized for hundreds of years title clinical pharmacology of cannabinoids in early phase drug development author zuurman hillie henka date issued 2008 05 28 access open access referencesclinical pharmacology of cannabinoids in early phase drug development ketamine challenge the psychoactive properties of several classes of drugs can be used to induce psychomimetic symptoms in healthy volunteers as a model for psychosis and antipsychotic drug action previous studies have used thc for this

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